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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48413Generated: October 28, 2026

2-Aminoindane → 4-(2-Indanylamino)-5-(2-thienyl)thieno[2,3-d]pyrimidine

https://huagongshe.com/reaction/48413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminoindaneHCID 76310—
Reactant4-Chloro-5-(2-thienyl)thieno[2,3-d]pyrimidineHCID 735732—
Product4-(2-Indanylamino)-5-(2-thienyl)thieno[2,3-d]pyrimidineHCID 12094063100%

Reaction Steps

Using 4-chloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (50 mg, 0.20 mmol) and 2-aminoindan (110 mg, 0.80 mmol), a similar procedure to Production Example 190 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=1:1) to obtain the title compound (70 mg, 0.20 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703421B1
Source datasetuspto-grants-2004_03
ORD IDord-af508c38ec2e46b0b21b9ae390a29200
Source noteuspto-grants-2004_03