HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminoindane → 4-(2-Indanylamino)-5-(2-thienyl)thieno[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminoindane | HCID 76310 | — |
| Reactant | 4-Chloro-5-(2-thienyl)thieno[2,3-d]pyrimidine | HCID 735732 | — |
| Product | 4-(2-Indanylamino)-5-(2-thienyl)thieno[2,3-d]pyrimidine | HCID 12094063 | 100% |
Reaction Steps
Using 4-chloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (50 mg, 0.20 mmol) and 2-aminoindan (110 mg, 0.80 mmol), a similar procedure to Production Example 190 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=1:1) to obtain the title compound (70 mg, 0.20 mmol) having the following physical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703421B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-af508c38ec2e46b0b21b9ae390a29200 |
| Source note | uspto-grants-2004_03 |