HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-[4-[1-(4-Fluorophenyl)-4-piperazinyl]butyl]-1,4-dioxothiazolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1,1-Dioxo-3-(4-(1-(4-fluorophenyl)-piperazin-4-yl)butyl)-2,5,5-trimethyl-4-thiazolidinone | HCID 18980396 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-[4-[1-(4-Fluorophenyl)-4-piperazinyl]butyl]-1,4-dioxothiazolidine | HCID 14856168 | 52.5% |
Reaction Steps
A second run using NaIO4 (1.41 g), H2O (13 ml), 1 (2.02 g) and THF (20 ml) was conducted in a similar manner yielding 0.910 g of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05229388 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-d44c54b9aa61448fad84e54ec069032e |
| Source note | uspto-grants-1993_07 |