HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane hydrochloride → 2-Amino-5-phenoxyindan hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Reactant | 2-(Tert-butoxycarbonylamino)-5-phenoxyindan | HCID 22719586 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Amino-5-phenoxyindan hydrochloride | HCID 22719615 | — |
Reaction Steps
Using 2-(tert-butoxycarbonylamino)-5-phenoxyindan (120 mg, 0.36 mmol), 4N hydrochloric acid-dioxane (1.7 ml) and acetic acid (5.1 ml), a similar procedure to Production Example 213 was carried out to obtain 2-amino-5-phenoxyindan hydrochloride (99 mg, 0.36 mmol) having the following physical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703421B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-269fb28bf0074a1c92198459c2a84f84 |
| Source note | uspto-grants-2004_03 |