HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane hydrochloride → N-benzyl-2-amino-5-indan carboxamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Reactant | N-benzyl-2-(tert-butoxycarbonylamino)-5-indan carboxamide | HCID 22719645 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-benzyl-2-amino-5-indan carboxamide hydrochloride | HCID 22719605 | — |
Reaction Steps
Using N-benzyl-2-(tert-butoxycarbonylamino)-5-indan carboxamide (820 mg, 2.2 mmol), 4N hydrochloric acid-dioxane (10 ml) and acetic acid (30 ml), a similar procedure to Production Example 213 was carried out to obtain N-benzyl-2-amino-5-indan carboxamide hydrochloride (660 mg, 2.2 mmol) having the following physical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703421B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-34e3df64b6094d4695de6fdcb50d62d6 |
| Source note | uspto-grants-2004_03 |