Anisole → Cyclopentyl(4-methoxyphenyl)methanone

HRID 484342Notes

Reaction equation

HRID 484342 reaction equation
[C:1]1([O:7][CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[Al+3].[Cl-].[Cl-].[CH:13]1([C:18](Cl)=[O:19])[CH2:17][CH2:16][CH2:15][CH2:14]1>>[CH:13]1([C:18]([C:4]2[CH:5]=[CH:6][C:1]([O:7][CH3:8])=[CH:2][CH:3]=2)=[O:19])[CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 7519AnisoleHCID 78284Cyclopentanecarbonyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 251071Cyclopentyl(4-methoxyphenyl)methanone

Procedure

In analogy to the procedure of Example I, the title compound is prepared from 31 g (0.287 mol) of anisole, 46 g (0.345 mol) of aluminium chloride and 40 g (0.302 mol) of cyclopentanecarbonyl chloride.

Sources & evidence

ORD record
ord-48a7cb0d88c84fd3bf2a7f3d74bea39a
Source dataset
uspto-grants-1993_07
Patent number
US05231103

Reaction notes

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