Hydroxyamine hydrochloride → 4(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketoxime

HRID 484349Notes

Reaction equation

HRID 484349 reaction equation
[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:12][CH:11]=2)=O)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[NH2:29][OH:30]>>[CH:1]1([C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:12][CH:11]=2)=[N:29][OH:30])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 200842384-(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketone

Product 1

HCID 736588494(Quinolin-2-yl-methoxy)phenyl cycloheptyl ketoxime

Procedure

In analogy to the procedure of Example IV, the title compound is prepared from 12.9 g (35.9 mmol) of the compound from Example XIII and 3.75 g (53.9 mmol) of hydroxylamine hydrochloride.

Sources & evidence

ORD record
ord-ced867d7d7f54b30abc599afcaadbe69
Source dataset
uspto-grants-1993_07
Patent number
US05231103

Reaction notes

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