4'-Hydroxyacetophenone → Ethyl 4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthoyloxy)benzoate

HRID 484366Notes

Reaction equation

HRID 484366 reaction equation
[CH3:1][C:2]1([CH3:26])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([C:14]([O:16][C:17]3[CH:22]=[CH:21][C:20]([C:23](=[O:25])C)=[CH:19][CH:18]=3)=[O:15])[CH:5]=[CH:4][C:3]1=2.[C:27](C1C=CC(O)=CC=1)(=[O:29])[CH3:28]>>[CH3:1][C:2]1([CH3:26])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([C:14]([O:16][C:17]3[CH:22]=[CH:21][C:20]([C:23]([O:29][CH2:27][CH3:28])=[O:25])=[CH:19][CH:18]=3)=[O:15])[CH:5]=[CH:4][C:3]1=2

Participants

3

Reactant 2

HCID 74694'-HydroxyacetophenoneHCID 19888663HCID 19888663, compound

Product 1

HCID 19748015Ethyl 4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthoyloxy)benzoate

Procedure

4-Acetylphenyl 5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthoate-Using 4-acetylphenol, the title compound was synthesized as a white solid. PMR (CDCl3): δ 1.36 (6H, s), 1.38 (6H, s), 1.76 (4H, s), 2.64 (3H, s), 7.34 (2H, d, J~8.4 Hz), 7.48 (1H, d, J~8.4 Hz), 7.98 (1H, dd, J~8.4 Hz, 2.4 Hz), 8.07 (2H, d, J~8.4 Hz), 8.19 (1H, d, J~2.4 Hz).

Sources & evidence

ORD record
ord-41abf808409541ccb263e3c6f2a8f1a4
Source dataset
uspto-grants-1993_07
Patent number
US05231113

Reaction notes

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