反应详情

A mixture of 4 g of N-[3-(bromomethyl)phenyl]-N'-[4-(tetradecyloxy)phenyl]urea and 2.3 g of 5-methylthiazole in 60 ml of tetrahydrofuran is refluxed for 4 hours. The solvent is evaporated, toluene added to the residue and evaporated to a residue. The residue is stirred with ether and the solid collected, washed with fresh ether and dried under vacuum to give 4.7 g of the desired product as a white powder, m.p. 165°-168° C.

1. temperatureis refluxed for 4 hours
2. customThe solvent is evaporated
3. additiontoluene added to the residue
4. customevaporated to a residue
5. customthe solid collected
6. washwashed with fresh ether
7. customdried under vacuum