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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 484762Generated: October 30, 2026

Ethoxy(6-phthalimidohexyl)phosphinyl chloride → (S)-3-[[ethoxy(6-phthalimidohexyl)phosphinyl]amino]-2-oxo-1-piperidineacetic acid, ethyl ester

https://huagongshe.com/reaction/484762

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthoxy(6-phthalimidohexyl)phosphinyl chlorideHCID 256577—
Reactant(S)-3-Amino-2-oxo-1-piperidineacetic acid, Ethyl esterHCID 13556450—
Product(S)-3-[[ethoxy(6-phthalimidohexyl)phosphinyl]amino]-2-oxo-1-piperidineacetic acid, ethyl esterHCID 86740217—

Reaction Steps

Ethoxy(6-phthalimidohexyl)phosphinyl chloride and (S)-3-amino-2-oxopiperidineacetic acid, ethyl ester are reacted according to the procedure of Example 1(g) to give (S)-3-[[ethoxy(6-phthalimidohexyl)phosphinyl]amino]-2-oxo-1-piperidineacetic acid, ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04533661
Source datasetuspto-grants-1985_08
ORD IDord-abfd7da1fbfd46b88c12907ff29a562e
Source noteuspto-grants-1985_08