Methanol → HCID 70466056, compound

HRID 484800Notes

Reaction equation

HRID 484800 reaction equation
[ClH:1].Cl.[CH3:3][C:4]1[CH:9]=[C:8]([NH2:10])[CH:7]=[CH:6][C:5]=1[NH:11][C:12]1[CH2:16][CH2:15][CH2:14][N:13]=1.[CH2:17]([O:19][CH2:20]C)C.C[OH:23]>>[ClH:1].[CH3:3][C:4]1[CH:9]=[C:8]([NH:10][C:17]([O:19][CH3:20])=[O:23])[CH:7]=[CH:6][C:5]=1[NH:11][C:12]1[CH2:16][CH2:15][CH2:14][N:13]=1

Participants

4

Reactant 3

HCID 887Methanol2×HCID 3283Diethyl EtherHCID 1317142942-[(2-Methyl-4-aminophenyl)amino]-1-pyrroline, dihydrochloride

Product 1

HCID 70466056HCID 70466056, compound

Procedure

The title compound was prepared by the method of Example 26 using the product compound of Example 9 and excess methanol. The crude product was dissolved in the minimum amount of methanol and treated with diethyl ether to point of cloudiness, then cooled. Insolubles were removed by filtration and the product forced out of the filtrate by addition of ether, giving the title compound as a solid. Structure assignment was supported by the nmr spectrum and by elemental analysis.

Workup

  1. temperaturecooled
  2. customInsolubles were removed by filtration
  3. additionthe product forced out of the filtrate by addition of ether

Sources & evidence

ORD record
ord-ccedf96272be4b909828136898c7e924
Source dataset
uspto-grants-1985_08
Patent number
US04533739

Reaction notes

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