HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-(2-Phenyl-5-isopropyl-4-oxazolyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 2-(2-phenyl-5-isopropyl-4-oxazolyl)acetate | HCID 13488807 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(2-Phenyl-5-isopropyl-4-oxazolyl)acetic acid | HCID 13488814 | 97.6% |
Reaction Steps
2.73 g of ethyl 2-(2-phenyl-5-isopropyl-4-oxazolyl)acetate, 20 ml of methanol, 5 ml of water and 1.1 g of potassium hydroxide are treated in the same manner as described in Example 8. 2.39 g of 2-(2-phenyl-5-isopropyl-4-oxazolyl)acetic acid are thereby obtained. Yield: 97.4%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04535089 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-b204aa53965e4d9fb3ccb7c43ef0fd10 |
| Source note | uspto-grants-1985_08 |