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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485014Generated: October 30, 2026

Methanol → [2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acid

https://huagongshe.com/reaction/485014

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantPotassium HydroxideHCID 14797—
ReactantEthyl [2-(4-chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetateHCID 13488812—
SolventWaterHCID 962—
Product[2-(4-Chlorophenyl)-5-pentyl-1,3-oxazol-4-yl]acetic acidHCID 1348881887.3%

Reaction Steps

1.0 g of ethyl 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetate, 10 ml of methanol, 3 ml of water and 0.4 g of potassium hydroxide are treated in the same manner as described in Example 8. 0.8 g of 2-[2-(4-chlorophenyl)-5-n-pentyl-4-oxazolyl]acetic acid are thereby obtained. Yield: 87.2%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04535089
Source datasetuspto-grants-1985_08
ORD IDord-0e3ca73e0316466884144eae2823e5c2
Source noteuspto-grants-1985_08