HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → Ethyl 3-benzoylamino-3-isobutyrylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(3-Methyl-2-oxobutyl)benzamide | HCID 13490305 | — |
| Product | Ethyl 3-benzoylamino-3-isobutyrylpropionate | HCID 13488802 | 67.8% |
Reaction Steps
6.8 g of N-benzoylisobutyrylmethylamine, 1.56 g of 61% sodium hydride and 6.1 g of ethyl bromoacetate are treated in the same manner as described in Preparation 1-(5). 6.54 g of ethyl 3-benzoylamino-3-isobutyrylpropionate are thereby obtained. Yield: 67.7%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04535089 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-e5fa86c8490d4acb89ebe9e2e7f982c0 |
| Source note | uspto-grants-1985_08 |