HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoyl chloride → N-(4-fluorobenzoyl)isobutyrylmethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-Amino-3-methylbutan-2-one hydrochloride | HCID 13401736 | — |
| Product | N-(4-fluorobenzoyl)isobutyrylmethylamine | HCID 13490306 | 89.4% |
Reaction Steps
4.0 g of isobutyrylmethylamine hydrochloride, 6.1 g of sodium bicarbonate and 5.1 g of 4-fluorobenzoyl chloride are treated in the same manner as described in Preparation 1-(4). 5.8 g of N-(4-fluorobenzoyl)isobutyrylmethylamine are thereby obtained. Yield: 89.2%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04535089 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-2b415b9ba8c64dc1b48f47c9afb60913 |
| Source note | uspto-grants-1985_08 |