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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485025Generated: October 30, 2026

4-Fluorobenzoyl chloride → 4-Fluoro-N-(4-methyl-2-oxopentyl)benzamide

https://huagongshe.com/reaction/485025

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
ReactantSodium BicarbonateHCID 516892—
Reactant1-Amino-4-methylpentan-2-one hydrochlorideHCID 13701755—
Product4-Fluoro-N-(4-methyl-2-oxopentyl)benzamideHCID 1349030893%

Reaction Steps

2.75 g of isovalerylmethylamine hydrochloride, 3.8 g of sodium bicarbonate and 3.16 g of 4-fluorobenzoyl chloride are treated in the same manner as described in Preparation 1-(4). 4.0 g of N-(4-fluorobenzoyl)isovalerylmethylamine are thereby obtained. Yield: 82.9%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04535089
Source datasetuspto-grants-1985_08
ORD IDord-f02114539136430da32867c9d46a0e75
Source noteuspto-grants-1985_08