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HRID485025

反应详情

EQUATION

反应方程式

HRID 485025 的结构方程式

REACTANTS

反应物

3
结构：O=C(Cl)c1ccc(F)cc1
HCID67879

Benzoyl chloride, 4-fluoro-

C7H4ClFO

结构：O=C([O-])O.[Na+]
HCID516892

Sodium Bicarbonate

CHNaO3

结构：CC(C)CC(=O)CN.Cl
HCID13701755

1-Amino-4-methylpentan-2-one--hydrogen chloride (1/1)

C6H14ClNO

PRODUCTS

生成物

1
结构：CC(C)CC(=O)CNC(=O)c1ccc(F)cc1
HCID13490308

4-Fluoro-N-(4-methyl-2-oxopentyl)benzamide

C13H16FNO2

收率 93%

PROCEDURE

实验过程

2.75 g of isovalerylmethylamine hydrochloride, 3.8 g of sodium bicarbonate and 3.16 g of 4-fluorobenzoyl chloride are treated in the same manner as described in Preparation 1-(4). 4.0 g of N-(4-fluorobenzoyl)isovalerylmethylamine are thereby obtained. Yield: 82.9%.

WORKUP

后处理

  1. customas described in Preparation 1-(4)