反应详情

A mixture of 30.0 g. of 4-(p-chlorocinnamamido)benzoic acid, ethyl ester, 500 mg. of 10% palladium on carbon, and 150 ml. of tetrahydrofuran is hydrogenated in a Parr apparatus, over a 2 hour period, repressurizing until hydrogen uptake is complete. The mixture is filtered, and the filtrate is evaporated. The solid is crystallized from 175 ml. of ethanol, giving 26.8 g. of the desired product as white crystals, m.p. 163°-165° C.

1. additionA mixture of 30.0 g
2. filtrationThe mixture is filtered
3. customthe filtrate is evaporated
4. customThe solid is crystallized from 175 ml
5. customof ethanol, giving 26.8 g