Water → HCID 20270153, compound

HRID 485302Notes

Reaction equation

HRID 485302 reaction equation
[C:1]1([O:11][CH2:12][CH2:13][CH2:14][CH2:15]Cl)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH3:17][O-:18].[Na+].O>CO>[C:1]1([O:11][CH2:12][CH2:13][CH2:14][CH2:15][O:18][CH3:17])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 962WaterHCID 10942334Sodium MethoxideHCID 20270163HCID 20270163, compound

Product 1

HCID 20270153HCID 20270153, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 4-(1-naphthyloxy)-butyl chloride (3.0 g) and sodium methoxide (1.5 g) in methanol (25 ml) was refluxed for 8 hours, then poured into water and the solution extracted with ether. The extract was dried and evaporated and the residue chromatographed on silica gel, eluting with 2:1 hexane ether, to produce the title compound as an oil.

Workup

  1. extractionthe solution extracted with ether
  2. customThe extract was dried
  3. customevaporated
  4. customthe residue chromatographed on silica gel
  5. washeluting with 2:1 hexane ether

Sources & evidence

ORD record
ord-8541c8ad32bb4f06a2ebc031d588f634
Source dataset
uspto-grants-1985_08
Patent number
US04536503

Reaction notes

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