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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485318Generated: October 30, 2026

Thionyl Chloride → HCID 13520516, compound

https://huagongshe.com/reaction/485318

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant3-[2-(5-Methyl-3-phenyl-1,2-oxazol-4-yl)-1H-indol-3-yl]propanoic acidHCID 13520515—
SolventTetrahydrofuranHCID 8028—
ProductHCID 13520516HCID 13520516—

Reaction Steps

A mixture of 5.1 g (0.0147 mole) of 2-(5-methyl-3-phenyl-4-isoxazolyl)-3-indole propionic acid and 7.0 g (0.059 mole) of thionyl chloride in 200 ml tetrahydrofuran is stirred for 18 hours at room temperature. The solvent is then removed in vacuo to give 2-(5-methyl-3-phenyl-4-isoxazolyl)-3-indole propionyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04536499
Source datasetuspto-grants-1985_08
ORD IDord-b84cd811f27d431a80e7eb7a49a081e8
Source noteuspto-grants-1985_08