Dimethylamine → HCID 20270114, compound

HRID 485319Notes

Reaction equation

HRID 485319 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[C:13]1[NH:14][C:15]2[C:20]([C:21]=1[CH2:22][CH2:23][C:24](Cl)=[O:25])=[CH:19][CH:18]=[CH:17][CH:16]=2.C(C1C(C2[NH:35][C:36]3[C:41]([C:42]=2[CH2:43][CH2:44]C(Cl)=O)=CC=CC=3)=C(C)ON=1)C.CNC.N1CCCC1>>[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[C:13]1[NH:14][C:15]2[C:20]([C:21]=1[CH2:22][CH2:23][C:24]([N:35]1[CH2:36][CH2:41][CH2:42][CH2:43][CH2:44]1)=[O:25])=[CH:19][CH:18]=[CH:17][CH:16]=2

Participants

5

Reactant 4

HCID 674DimethylamineHCID 31268PyrrolidineHCID 13520516HCID 13520516, compoundHCID 86740256HCID 86740256, compound

Product 1

HCID 20270114HCID 20270114, compound

Procedure

Also, following the above procedure and using in place of 2-(5-methyl-3-phenyl-4-isoxazolyl)-3-indole propionyl chloride an equivalent amount of 2-(3-ethyl-5-methyl-4-isoxazolyl)-3-indole propionyl chloride and using in place of dimethylamine an equivalent amount of pyrrolidine there is obtained

Workup

  1. customthere is obtained

Sources & evidence

ORD record
ord-7b79542cc7cb47e2901c7d445f572712
Source dataset
uspto-grants-1985_08
Patent number
US04536499

Reaction notes

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