HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → Ethyl 3-(1h-indol-3-yl)propanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | 1H-Indole-3-propanoic acid | HCID 3744 | — |
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Produkt | Ethyl 3-(1h-indol-3-yl)propanoate | HCID 225390 | — |
Reaktionsschritte
A solution of 7.38 g of 3-indolepropionic acid and 5.9 g of thionyl chloride in 50 ml of ethanol is refluxed for 2 hours, cooled and evaporated. The residue is partitioned between ether and cold sodium bicarbonate solution. The organic phase is separated, dried over sodium sulfate and evaporated to yield ethyl 3-(3-indolyl)propionate; Rf (ether/SiO2)=0.51; IR (CH2Cl2) 1725 cm-1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04536505 |
| Quelldatensatz | uspto-grants-1985_08 |
| ORD ID | ord-5994383167854f419bf372b83aea7c1e |
| Quellennotiz | uspto-grants-1985_08 |