Aluminum(III) Chloride → HCID 13072182, compound

HRID 485365Notes

Reaction equation

HRID 485365 reaction equation
[Al+3].[Cl-].[Cl-].[Cl-].[C:5]1([CH:11](O)[CH2:12][N:13]2[CH:17]=[N:16][CH:15]=[N:14]2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>C1C=CC=CC=1.ClCCCl>[C:5]1([CH:11]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH2:12][N:13]2[CH:17]=[N:16][CH:15]=[N:14]2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

5

Reactant 2

HCID 6451240Aluminum(III) ChlorideHCID 10081198HCID 10081198, compound

Product 1

HCID 13072182HCID 13072182, compound

Reagents, catalysts & solvents 2

HCID 111,2-DichloroethaneSolventHCID 241BenzeneSolvent

Procedure

26.7 g (0.2 mole) of AlCl3 were added in portions to a solution of 18.9 g (0.1 mole) of 1-phenyl-2-(1,2,4-triazol-1-yl)-ethanol in 50 ml of benzene and 50 ml of 1,2-dichloroethane at -10° C. Thereafter, the mixture was warmed to room temperature in the course of 30 minutes, and was then heated to 80° C., until the evolution of gas was no longer observed. The mixture was poured onto 200 ml of ice-water, the organic phase was separated off and concentrated, and the residue was triturated with diisopropyl ether. Yield 21.4 g (86% ), m.p. 107°-108° C.

Workup

  1. temperaturewas then heated to 80° C., until the evolution of gas
  2. customthe organic phase was separated off
  3. concentrationconcentrated
  4. customthe residue was triturated with diisopropyl ether

Sources & evidence

ORD record
ord-c4b3ec3a748149978576743aadf26d16
Source dataset
uspto-grants-1985_08
Patent number
US04536509

Reaction notes

Loading…