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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485397Generated: October 29, 2026

1-(4-Hydroxyphenyl)-2-phenylbutan-1-one → 1-(4-Methoxyphenyl)-2-phenylbutan-1-one

https://huagongshe.com/reaction/485397

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Hydroxyphenyl)-2-phenylbutan-1-oneHCID 227278—
Reactant4-(beta-Dimethylaminoethoxy)-alpha-methyldesoxybenzoinHCID 70479849—
Product1-(4-Methoxyphenyl)-2-phenylbutan-1-oneHCID 3642181—

Reaction Steps

4-(β-Dimethylaminoethoxy)-α-ethyldesoxybenzoin (b.p. 162° C./0.075 mm.) may be obtained from α-ethyl-4-hydroxydesoxybenzoin by an analogous procedure to that described below for the preparation of 4-(β-dimethylaminoethoxy)-α-methyldesoxybenzoin, and α-ethyl-4-hydroxydesoxybenzoin itself (m.p. 122°-124° C.) may be obtained from α-ethyl-4-methoxydesoxybenzoin by an analogous procedure to that described below for the preparation of 4-hydroxy-α-methyldesoxybenzoin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04536516
Source datasetuspto-grants-1985_08
ORD IDord-74f512026c40454b863dc61d6094d425
Source noteuspto-grants-1985_08