Benzene → HCID 13490382, compound

HRID 485412Notes

Reaction equation

HRID 485412 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[CH:11](O)[CH2:10][C:9]3[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=3[S:7][C:6]=2[CH:17]=1.C1C=CC=CC=1.C1(C)C=CC(S(O)(=O)=O)=CC=1>O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[CH:11]=[CH:10][C:9]3[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=3[S:7][C:6]=2[CH:17]=1

Participants

5

Reactant 3

HCID 241BenzeneHCID 6101p-Toluenesulfonic acidHCID 20270227HCID 20270227, compound

Product 1

HCID 13490382HCID 13490382, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

17 G. 3-bromo-11-hydroxy-10,11-dihydrodibenzo[b,f]thiepin are dissolved in 600 cc. benzene; 1 gram p-toluene sulfonic acid is added and the mixture is refluxed with elimination of water for two hours. The solution is cooled and washed with aqueous sodium bicarbonate solution and water, dried and stripped to a solid residue. 16 G. of 3-bromodibenzo[b,f]thiepin are obtained.

Workup

  1. temperatureThe solution is cooled
  2. washwashed with aqueous sodium bicarbonate solution and water
  3. customdried

Sources & evidence

ORD record
ord-54e83c74f28945e9930f9d9fcaed62d6
Source dataset
uspto-grants-1985_08
Patent number
US04536507

Reaction notes

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