Potassium Hydroxide → HCID 13151846, compound

HRID 485435Notes

Reaction equation

HRID 485435 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([SH:8])[CH:5]=[CH:6][CH:7]=1.[OH-].[K+].Cl[C:12]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][C:13]=1[C:14]([OH:16])=[O:15]>[Cu].O>[Br:1][C:2]1[CH:3]=[C:4]([S:8][C:12]2[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][C:13]=2[C:14]([OH:16])=[O:15])[CH:5]=[CH:6][CH:7]=1

Participants

6

Reactant 3

HCID 14797Potassium HydroxideHCID 172872-Chloro-5-nitrobenzoic acidHCID 80597m-Bromobenzenethiol

Product 1

HCID 13151846HCID 13151846, compound

Reagents, catalysts & solvents 2

HCID 23978CopperCatalystHCID 962WaterSolvent

Procedure

A mixture of 205 g. 3-bromothiophenol, 188 g. potassium hydroxide in 2 l. water, 205 g. 2-chloro-5-nitrobenzoic acid and 6.5 g. copper powder is refluxed for two hours, filtered while hot, acidified with hydrochloric acid and the solid filtered, washed with water and dried to yield 301 g. of the desired white solid, m.p. 202°-206° C.

Workup

  1. additionA mixture of 205 g
  2. filtrationfiltered while hot,
  3. filtrationthe solid filtered
  4. washwashed with water
  5. customdried
  6. customto yield 301 g

Sources & evidence

ORD record
ord-a1218ce042344b9fabf2d62df958b0af
Source dataset
uspto-grants-1985_08
Patent number
US04536507

Reaction notes

Loading…