反应详情

400 Mg. 3-cyano-8-nitrodibenzo[b,f]-thiepin-5,5-dioxide is refluxed in 5 cc. acetic acid and 5 cc. 50% aqueous sulfuric acid for 24 hours. The mixture is cooled down, the crystallized material is filtered, washed with water, dried at 135° C. in vacuum to yield 345 mg. (81.2%) acid, m.p. 310°-312° C.

1. temperatureThe mixture is cooled down
2. filtrationthe crystallized material is filtered
3. washwashed with water
4. customdried at 135° C. in vacuum
5. customto yield 345 mg