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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485498Generated: October 30, 2026

Dimethyl malonate → HCID 178437790, compound

https://huagongshe.com/reaction/485498

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl malonateHCID 7943—
ReactantHCID 12301254HCID 12301254—
SolventSodium MethoxideHCID 10942334—
ProductHCID 178437790HCID 17843779089.5%

Reaction Steps

Using the procedure of Example 1, Part B1, 18.5 g (0.14 mole) of propionamidine acetate and 90 ml of 25% sodium methoxide were reacted with dimethyl malonate (0.14 mole) to provide 16.5 g (89.5%) of 4,6-dihydroxy-2ethylpyrimidine according to Step (1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04536579
Source datasetuspto-grants-1985_08
ORD IDord-34d580d67bef4d9c9b06435ad359997f
Source noteuspto-grants-1985_08