2,4,5-Trichlorophenol → HCID 14217445, compound

HRID 485626Notes

Reaction equation

HRID 485626 reaction equation
[C:1](Cl)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[Cl:13][C:14]1[CH:19]=[C:18]([Cl:20])[C:17]([Cl:21])=[CH:16][C:15]=1[OH:22]>C(OCC)C.N1C=CC=CC=1>[C:1]([O:22][C:15]1[CH:16]=[C:17]([Cl:21])[C:18]([Cl:20])=[CH:19][C:14]=1[Cl:13])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

5

Reactant 2

HCID 72712,4,5-TrichlorophenolHCID 66982Decanoyl chloride

Product 1

HCID 14217445HCID 14217445, compound

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 3283Diethyl EtherSolvent

Procedure

A solution of decanoyl chloride (Pfaltz and Bauer, 5.6 ml) and 2,4,5-trichlorophenol (5.6 g) in diethyl ether (1 L) and pyridine (120 ml) is stirred for 4 hours. The reaction mixture is filtered and dried in vacuo. The 2,4,5-trichlorophenyl n-decanoate is purified on a silica-gel column (Woelm), using toluene as the eluent. Fractions are monitored by TLC, using short-wave UV for detection. Appropriate fractions are pooled and dried in vacuo to give 10.4 g of 2,4,5-trichlorophenyl n-decanoate.

Workup

  1. filtrationThe reaction mixture is filtered
  2. customdried in vacuo
  3. customThe 2,4,5-trichlorophenyl n-decanoate is purified on a silica-gel column (Woelm)
  4. customdried in vacuo

Sources & evidence

ORD record
ord-a97eef46b2a74b40b2ca06c8268d54d3
Source dataset
uspto-grants-1985_08
Patent number
US04537717

Reaction notes

Loading…