(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile → HCID 131714315, compound

Participants

Reaction Steps

Using the procedure of Example 1, 0.6 g of the acid of Step C of Example 27 and 0.73 g of (S)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain 1.0 g of (S)α-cyano-3-phenoxybenzyl (1R,trans) 2,2-dimethyl-3-(3-chloro-1,2-propadienyl)cyclopropane-carboxylate with a specific rotation of [α]D20 =+26°±2° (c=0.75% in CHCl3).

Provenance & Evidence