HCID 178519539, compound → HCID 178507498, compound

Participants

Reaction Steps

To 4.2 g. of 1(o-benzylaminobenzoyl)-1H-indazol-3-ol dissolved in 1 liter of absolute EtOH was added 1.4 g of 10% Pd/C and the mixture was hydrogenated in a Paar apparatus for 16 hrs. The catalyst was then filtered off, washed well with EtOH, and the filtrate evaporated to afford 2.3 g. of a yellow-green solid. Recrystallization from aqueous. EtOH afforded the desired amine as a light yellow solid in 66.7% yield; m.p. 181°-183° C.

Provenance & Evidence