Trimethylsilylacetylene → 3-(Trimethylsilyl)ethynylbenzaldehyde

HRID 485774Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6].[C:10]([Si:12]([CH3:15])([CH3:14])[CH3:13])#[CH:11]>>[CH3:13][Si:12]([C:10]#[C:11][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6])([CH3:15])[CH3:14]

Participants

Reactant 2

HCID 66111Trimethylsilylacetylene

HCID 765833-Bromobenzaldehyde

Product 1

HCID 27716423-(Trimethylsilyl)ethynylbenzaldehyde

Procedure

Compound VI was synthesized by the organopalladiumcatalyzed ethynylation of meta-bromobenzaldehyde with ethynyltrimethylsilane as follows: ##STR4##

Sources & evidence

ORD record: ord-22c26a963f5940f5b6cd74ebcb23944b
Source dataset: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04537974

Reaction notes

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