Homoveratrylamine → N-[2-(3,4-Dimethoxy-phenyl)-ethyl]-3,4-difluorophenyl-acetamide

HRID 48585Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][NH2:13])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[F:14][C:15]1[CH:16]=[C:17]([CH2:22][C:23](O)=[O:24])[CH:18]=[CH:19][C:20]=1[F:21]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][NH:13][C:23](=[O:24])[CH2:22][C:17]2[CH:18]=[CH:19][C:20]([F:21])=[C:15]([F:14])[CH:16]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

Reactant 2

HCID 8421Homoveratrylamine

HCID 69571(3,4-Difluorophenyl)acetic acid

Product 1

HCID 22742856N-[2-(3,4-Dimethoxy-phenyl)-ethyl]-3,4-difluorophenyl-acetamide

Procedure

prepared by reaction of 3,4-dimethoxyphenylethylamine and 3,4-difluorophenylacetic acid.

Sources & evidence

ORD record: ord-88eefec4fb5a45338ffced616d924f25
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06703392B2

Reaction notes

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