HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-1-phenylethan-1-one → 2-Bromo-2-fluoro-1-phenylethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-1-phenylethan-1-one | HCID 9947 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-Bromo-2-fluoro-1-phenylethan-1-one | HCID 12545127 | — |
Reaction Steps
To a solution of 2.76 g of 2-fluoroacetophenone in 50 ml of ether is added dropwise over 30 minutes a solution of 3.2 g of bromine in 10 ml of chloroform. Evaporation of the reaction mixture under reduced pressure affords α-bromo-2-fluoroacetophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04537976 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-91fefa60659740b49cc3e268c3565548 |
| Source note | uspto-grants-1985_08 |