HRID48594

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8355

1-Naphthalenemethanamine

C11H11N

HCID61147

Acetyl bromide, 2-bromo-

C2H2Br2O

HCID12950740

未命名化合物

PRODUCTS

生成物

结构：COc1ccc2c(c1)CCN(CC(=O)NCc1cccc3ccccc13)C2Cc1ccc(OC)c(OC)c1

HCID22742829

未命名化合物

PROCEDURE

实验过程

prepared by reaction of 1-(3,4-dimethoxy-benzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 1-napthalenemethylamine

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7a28fddb900942baafce1689f0f0fa03
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06703392B2
来源说明: uspto-grants-2004_03

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:6][CH:7]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=2)[CH2:10][CH2:9][NH:8]1.Br[CH2:25][C:26](Br)=[O:27].[C:29]1([CH2:39][NH2:40])[C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:32]=[CH:31][CH:30]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:6][CH:7]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=2)[CH2:10][CH2:9][N:8]1[CH2:25][C:26]([NH:40][CH2:39][C:29]1[C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:32]=[CH:31][CH:30]=1)=[O:27]