Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4,6-Dimethoxy-2-(methylsulfonyl)pyrimidine | HCID 838363 | — |
| Reactant | HCID 19097218 | HCID 19097218 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19097220 | HCID 19097220 | — |
Reaction Steps
At 10° C., 0.30 g (0.01 mol) of sodium hydride (80% strength) is added to a solution of 3.35 g (10 mmol) of 3-(4-bromophenyl)-2-(N,N-dimethylaminooxycarbonyl)-phenol in 25 ml of dried dimethylformamide, and the mixture is stirred for 3 hours at 30° C. Subsequently, 2.18 g (0.01 mol) of 2-methylsulfonyl-4,6-dimethoxypyrimidine is added and the mixture stirred for 12 hours at room temperature. Working up in accordance with Example 4 gives a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05290755 |
|---|
| Source dataset | uspto-grants-1994_03 |
|---|
| ORD ID | ord-20d699bfc4d14f6d88aa319512932139 |
|---|
| Source note | uspto-grants-1994_03 |
|---|
