Hydrogen Peroxide → HCID 15746740, compound

HRID 486335Notes

Reaction equation

HRID 486335 reaction equation
[C:1]([NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([OH:17])=[O:16])(=[O:3])[NH2:2].[OH:18]O.O>S(=O)(=O)(O)O>[C:1]([NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([O:17][OH:18])=[O:16])(=[O:3])[NH2:2]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 1574673911-[(Aminocarbonyl)amino]undecanoic acid

Product 1

HCID 15746740HCID 15746740, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Conditions

Temperature
15 °C

Procedure

61.6 g (0.25 mol) of N-carbamoyl-11-aminoundecanoic acid are dissolved in 74.4 g of sulfuric acid (96% strength by weight) and the solution is cooled to 15° C. 23.8 g (0.6 mol) of hydrogen peroxide (85% strength by weight) are added dropwise with cooling at such a rate that the internal temperature can be maintained between 15 and 20° C. The reaction mixture is subsequently stirred with occasional cooling at 20° C. internal temperature for 1 h and then cooled down to 10° C., 200 ml of water are added dropwise, and the precipitated peroxycarboxylic acid is filtered off with suction. The filter cake is washed with water until free of mineral acid and is dried at 40° C. under an aspirator vacuum.

Workup

  1. temperaturewith cooling at such a rate that the internal temperature
  2. temperaturecan be maintained between 15 and 20° C
  3. temperaturewith occasional cooling at 20° C. internal temperature for 1 h
  4. temperaturecooled down to 10° C.
  5. filtrationthe precipitated peroxycarboxylic acid is filtered off with suction
  6. washThe filter cake is washed with water until free of mineral acid
  7. customis dried at 40° C. under an aspirator vacuum

Sources & evidence

ORD record
ord-4191ccdb285e450a9ae4692b4b2a98eb
Source dataset
uspto-grants-1994_03
Patent number
US05292451

Reaction notes

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