HCID 53635372, compound → HCID 53700867, compound

Participants

Reaction Steps

A solution of (R)-3-quinuclidinyl 2-phenyl-3-(pyrazin-2-yl)acrylate (see Preparation 4) (350 mg) in ethanol (20 ml) containing 10% palladium-on-carbon (30 mg) was stirred for 24 hours under an atmosphere of hydrogen [344.7 kPa (50 psi)] at room temperature. The mixture was filtered and evaporated to leave the title compound as an oil (320 mg, 91%).

Provenance & Evidence