反应详情

A mixture of 3.202 g of 2-butyl-1,4-dihydro-4-oxo-6-quinazolinecarboxaldehyde and 5.093 g of (carbethoxymethylene)triphenylphosphorane in 50 ml of acetonitrile is heated at reflux for 18 hours. The reaction mixture is cooled and the resulting solid washed with ether and dried to give 1.94 g of the desired product. CI MASS SPEC 301 (MH+)

1. temperatureis heated
2. temperatureat reflux for 18 hours
3. temperatureThe reaction mixture is cooled
4. washthe resulting solid washed with ether
5. customdried