Methyl iodide → HCID 19095281, compound

HRID 486568Notes

Reaction equation

HRID 486568 reaction equation
[CH3:1][C:2]1[C:3]2[N:4]([C:8]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:9][CH:10]=2)[CH2:5][CH2:6][N:7]=1.[CH3:17][I:18]>C(O)C>[I-:18].[CH3:1][C:2]1[C:3]2[N:4]([C:8]([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)=[CH:9][CH:10]=2)[CH2:5][CH2:6][N+:7]=1[CH3:17]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19095264HCID 19095264, compound

Product 1

HCID 19095281HCID 19095281, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3,4-Dihydro-1-methyl-6-phenylpyrrolo[1,2-a]pyrazine (0.6 g) was dissolved in 10 ml of ethanol and treated with 0.9 ml of methyl iodide under argon. The solution was boiled overnight, cooled and the separated crystals were filtered off. There was obtained 0.8 g (78%) of 3,4-dihydro-1,2-dimethyl-6-phenylpyrrolo[1,2-a]pyrazinium iodide; m.pt.: 213°-216° C. (dec.).

Workup

  1. temperaturecooled
  2. filtrationthe separated crystals were filtered off

Sources & evidence

ORD record
ord-786d687a092c4f1cadf2ce95761b51cc
Source dataset
uspto-grants-1994_03
Patent number
US05292732

Reaction notes

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