Sodium Hydroxide → HCID 86747631, compound

Participants

Reaction Steps

The compound 121 obtained above (3.90 g, 9.27 mmole) was dissolved in methanol (40 ml), and 10% aqueous sodium hydroxide was added to the solution, and the mixture was stirred at room temperature for one hour. Then, the mixture was treated following the procedure similar to that of Example 44 to yield a residue (2.84 g). The residue was purified with Lobar column (ethyl acetate:n-hexane:acetic acid=50:50:1), to yield the title compound 122 (2.67 g, 84%).

Provenance & Evidence