Isatoic Anhydride → HCID 15293864, compound

Participants

Role	Name	HCID	Charge
Reactant	Isatoic Anhydride	HCID 8359	—
Reactant	N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide	HCID 3035714	—
Catalyst	4-(Dimethylamino)pyridine	HCID 14284	—
Solvent	Dimethylformamide	HCID 6228	—
Product	HCID 15293864	HCID 15293864	75.5%

Reaction Conditions

Temperature	80 °C

Reaction Steps

500 mg (1.35 mmol) of the compound of Example 6, 260 mg (1.59 mmol) of isatoic anhydride and 170 mg (1.39 mmol) of 4-dimethylaminopyridine were dissolved in 5 ml of dimethylformamide and the solution was stirred at 80° C. for 5 h. The solvent was distilled off under reduced pressure and ethyl acetate was added to the residue. A precipitate thus formed was recrystallized from ethanol to obtain 500 mg of the title compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05292758
Source dataset	uspto-grants-1994_03
ORD ID	ord-662d0a8dcbff423e9672c5d8c673ea78
Source note	uspto-grants-1994_03