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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 486641Generated: October 29, 2026

4-tert-Butylbenzenesulfonamide → N-[5-(1,3-benzodioxol-5-yloxy)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-p-tert-butylbenzenesulfonamide

https://huagongshe.com/reaction/486641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-ButylbenzenesulfonamideHCID 222872—
ReactantHCID 19095638HCID 19095638—
ProductN-[5-(1,3-benzodioxol-5-yloxy)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-p-tert-butylbenzenesulfonamideHCID 19095801—

Reaction Steps

By reacting 5-(1,3-benzodioxol-5-yloxy)-4,6-dichloropyrimidine with p-tert-butylphenylsulfonamide and thereafter with ethylene glycol Na, there was obtained N-[5-(1,3-benzodioxol-5-yloxy)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-p-tert-butylbenzenesulfonamide as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05292740
Source datasetuspto-grants-1994_03
ORD IDord-7d40bf7d9ae0433aa62c3e1b7bb1b996
Source noteuspto-grants-1994_03