HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxybenzene-1-sulfonamide → N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-4-pyrimidinyl]-o-methoxybenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxybenzene-1-sulfonamide | HCID 4739144 | — |
| Reactant | 4,6-Dichloro-5-(2-methoxyphenoxy)pyrimidine | HCID 15819130 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-4-pyrimidinyl]-o-methoxybenzenesulfonamide | HCID 19095758 | — |
Reaction Steps
By reacting 5-(2-methoxyphenoxy)-4,6-dichloropyrimidine with o-methoxyphenylsulfonamide and thereafter with ethylene glycol Na, there was obtained N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-4-pyrimidinyl]-o-methoxybenzenesulfonamide, m.p. 164°-165° C. (from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05292740 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-d020c6f8d33249919cbcf9822ab9fa85 |
| Source note | uspto-grants-1994_03 |