Trifluoroacetic acid → HCID 54063270, compound

Participants

Reaction Steps

To a stirred solution of trans-2-acetylthiomethyl-4-tert-butoxycarbonyltetrahydrothiophene (compound No. 4-1, 130 mg) in methylene chloride (2 ml), trifluoroacetic acid (1 ml) was added and the mixture was stirred for 2 hours at room temperature. The mixture was concentrated in vacuo and the oily residue was purified by a silica gel column chromatography to give 112 mg (quantitative yield) of the titled compound (compound No. 6-1) as white powder.

Provenance & Evidence