Hydrochloric Acid → HCID 54060056, compound

Participants

Reaction Steps

To a stirred solution of cis-4-(1-mercapto-1-methylethyl)-2-mercaptomethyl-4-butanolide (1.1 g) in THF (4 ml), 1N sodium hydroxide solution (5.2 ml) was added and the mixture was stirred for 30 minutes. The reaction mixture was acidified with 1N hydrochloric acid and extracted with ethyl acetate. The organic layer was washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated in vacuo to give the titled compound (compound No. 8-1) quantitatively.

Provenance & Evidence