HRID48673

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID61147

Acetyl bromide, 2-bromo-

C2H2Br2O

HCID123465

2-Ethoxybenzylamine

C9H13NO

结构：COc1ccc(OC)c(CC2NCCc3c(OC)ccc(OC)c32)c1

HCID22742709

未命名化合物

PRODUCTS

生成物

结构：CCOc1ccccc1CNC(=O)CN1CCc2c(OC)ccc(OC)c2C1Cc1cc(OC)ccc1OC

HCID22742748

未命名化合物

PROCEDURE

实验过程

prepared by reaction of 1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-ethoxy-benzyl-amine

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ce63690cf4294586a24ed6b6ceb057e1
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06703392B2
来源说明: uspto-grants-2004_03

反应 SMILES

[CH3:1][O:2][C:3]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:4]=1[CH2:5][CH:6]1[C:15]2[C:10](=[C:11]([O:18][CH3:19])[CH:12]=[CH:13][C:14]=2[O:16][CH3:17])[CH2:9][CH2:8][NH:7]1.Br[CH2:27][C:28](Br)=[O:29].[CH2:31]([O:33][C:34]1[CH:41]=[CH:40][CH:39]=[CH:38][C:35]=1[CH2:36][NH2:37])[CH3:32]>>[CH3:1][O:2][C:3]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:4]=1[CH2:5][CH:6]1[C:15]2[C:10](=[C:11]([O:18][CH3:19])[CH:12]=[CH:13][C:14]=2[O:16][CH3:17])[CH2:9][CH2:8][N:7]1[CH2:27][C:28]([NH:37][CH2:36][C:35]1[CH:38]=[CH:39][CH:40]=[CH:41][C:34]=1[O:33][CH2:31][CH3:32])=[O:29]