Acetic Anhydride → HCID 54572216, compound

Participants

Reaction Steps

trans-4-carboxy-2-(1-mercapto-1-methylethyl)tetrahydrothiophene (compound No. 8-1, 50 mg) was dissolved in a mixture of acetic anhydride (1 ml) and pyridine (1 ml) and the mixture was stirred over night at room temperature. The reaction mixture was concentrated in vacuo and the oily residue was purified by a silica gel column chromatography to give 43 mg (72%) of the titled compound (compound No. 13-1).

Provenance & Evidence