Diazomethane → HCID 54458810, compound

Participants

Reaction Steps

Diethylether solution of diazomethane (10 molar equivalents) was added to trans-4-ethoxycarbonyl-2-mercaptomethyltetrahydrothiophene (compound No. 15-1, 549 mg) and the mixture was stirred for 4 hours at room temperature. The mixture was concentrated in vacuo and the oil residue was purified by a silica gel column chromatography to give 407 mg (69%) of the titled compound (compound No. 18-1).

Provenance & Evidence