反应详情

A mixture of 7.86 g. (50.0 mmole) of dipentylamine, 18.05 ml (50.0 mmole) of 2.77M NaOH solution and 60 ml of toluene was vigorously stirred at -7° to -5° C., and 60 ml (115.8 mmole) of 1.93M phosgene in toluene was added dropwise over 1 hour. After stirring an additional 30 min., the cold mixture was separated and the toluene layer was dried over solid NaCl. After filtering, nitrogen was bubbled through the solution for 1 hour and the solution was concentrated in vacuo to 10.5 g. (95%) of light yellow oil.

1. additionA mixture of 7.86 g
2. customthe cold mixture was separated
3. dry with materialthe toluene layer was dried over solid NaCl
4. filtrationAfter filtering
5. customnitrogen was bubbled through the solution for 1 hour
6. concentrationthe solution was concentrated in vacuo to 10.5 g