Dicyclohexylcarbodiimide → HCID 19096843, compound

HRID 487025Notes

Reaction equation

HRID 487025 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[CH:10]([NH:12][CH:13]([C:19]([O-])=[O:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15])=[O:11].C1(N=C=NC2CCCCC2)CCCCC1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][C:19](=[O:20])[CH:13]([NH:12][CH:10]=[O:11])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:6]=[C:7]([Cl:9])[CH:8]=1

Participants

4

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 122813,5-DichloroanilineHCID 85670808HCID 85670808, compound

Product 1

HCID 19096843HCID 19096843, compound

Procedure

3,5-Dichloroaniline, mono-ethyl formamidomalonate and 1,3-dicyclohexylcarbodiimide were reacted in a manner similer to that described in Example XCI Part B to give ethyl 3-[(3,5-dichlorophenyl)amino]-2-formamido-3-oxopropanoate having a melting point of 147.0° C.-148.0° C. Elemental analysis of the product indicated the following:

Sources & evidence

ORD record
ord-1b88c239ab4c47ea84d1e83e0a7167a1
Source dataset
uspto-grants-1994_03
Patent number
US05292937

Reaction notes

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